Glucose Intolerance : Definition and Risk Factors

tipstipskehamilan. Glucose intolerance represents a metabolic conditions which result in higher than normal blood glucose levels known as hyperglycemia. Glucose intolerance also means conditions where the body is not processing glucose as it should leading to elevated glucose levels in the blood. Type 1 and type 2 diabetes mellitus, gestational diabetes mellitus, impaired glucose tolerance and impaired fasting glucose are several categories of glucose intolerance.

Glucose Intolerance Definition
Glucose intolerance occurs when the body isn't able to process sugar well. Chronic high levels of blood sugar or glucose trigger the pancreas releases more insulin, leading to higher insulin levels (hyperinsulinemia).

When the immune system sends antibodies to destroy the insulin-producing cells in the pancreas, the body cannot produce insulin which leads to a very high level of blood sugar and associated complications and type 1 diabetes develops.

When the body fails to properly use insulin or the body's cells don't respond normally to the insulin the body produces, it is means insulin resistance occurs . When this happens, insulin can’t to move the sugar into the cells of the body, sugar builds up in the blood and rises and type 2 diabetes develops.

When the placenta produces hormones to takes over the support and growth of the foetus (baby in the womb) during pregnancy, the high levels of hormones impede with the body's natural response to insulin and insulin resistance occurs.

If this happens, insulin can’t to move the sugar into the cells of the body. When glucose can not leave the blood and be changed to energy, glucose builds up in the blood to high levels and causes gestational diabetes.

Gestational diabetes may reverse on its own after pregnancy, but type 1 and type 2 diabetes mellitus are usually permanent. But when a woman had gestational diabetes in a previous pregnancy, she have a 60 percent chance of developing it again in the next pregnancy and puts the woman at a higher risk of developing Type 2 diabetes later in life.

When blood glucose is raised beyond the normal range, it might causes impaired glucose tolerance. But it is not so high that a person have impaired glucose tolerance have diabetes. However, impaired glucose tolerance can increase the risk of developing diabetes and the risk of developing cardiovascular disease (heart disease, peripheral vascular disease and stroke).

When a person has elevated blood sugar (blood glucose) in the morning before eating or drinking, it might causes fasting blood sugar levels are not normal and causes impaired fasting glucose. But it is not high enough to be classified as diabetes.
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